Introduction: Achieving a successful pregnancy post solid organ transplant is a balance between adequate immunosuppression to preserve graft function and minimizing the patient’s immunosuppression to prevent harm to both the patient and fetus. There is ample data and published clinical guidelines for pregnancy post renal and other solid organ transplants, but no such guidelines exist in the literature for pregnancy in lung transplant recipients. To date, management of pregnancies in lung transplant recipients is based on small case series, the National Transplant Pregnancy Registry (NTPR) data reports and extrapolated from the outcomes and experience of other solid organ transplant recipient pregnancies. This includes pre-conception counselling of the risks involved in the pregnancy to both the mother and the fetus but makes it difficult to counsel women on the effects of pregnancy on longer-term transplant lung function, maternal and foetal outcomes.
Method: Our retrospective case series will characterise the Queensland experience of pregnancy in lung transplant recipients to improve the quality of our pre-conception counselling.
Conclusion: Results will be presented of a small, local case series of female (N=5) lung transplant recipients who have been pregnant. Lung function data in particular will be compared to a control group (N=5) female lung transplant recipients who have not been pregnant, to assess donor lung organ function during the peri partum period to evaluate whether it declines compared to a control group. Foetal and maternal data will also be evaluated to assess risk of pregnancy and improve prenatal counselling for future pregnancies.